Domenico Mazzocchi (baptised 1592 in Civita Castellana – 21/01/1665 in Veja) was an Italian Baroque composer of only vocal music, of the generation after Claudio Monteverdi. He was a learned Roman lawyer, studied music with Giovanni Maria Nanino (or Nanini), also in Rome, and entered the service of cardinal Ippolito Aldobrandini in 1621. He is associated with providing music for the popes, particularly Cardinal Maffeo Barberini, later Pope Urban VIII, until Mazzocchi's death in Rome on 21 January 1665. His younger brother, Virgilio Mazzocchi, was a less notable Roman composer and had a similar career as a Vatican music provider.